C1QA antibody (C-Term)

Catalog No. ABIN2841459

Product Details anti-C1QA Antibody

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Binding Specificity: AA 198-227, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human C1QA.

Clone: RB18692

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: C1QA (C1QA Products)

Synonyms: zgc:109903 antibody, C1QA antibody, AI255395 antibody, C1q antibody, complement C1q A chain antibody, complement component 1, q subcomponent, A chain antibody, complement component 1, q subcomponent, alpha polypeptide antibody, C1QA antibody, c1qa antibody, C1qa antibody

Background: C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.

Molecular Weight: 26017

Gene ID: 712

NCBI Accession: NP_057075

UniProt: P02745

Pathways: Complement System