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PDGFRA antibody (AA 746-775)

PDGFRA Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB11119 unconjugated
Catalog No. ABIN2841801
  • Target See all PDGFRA Antibodies
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Binding Specificity
    • 23
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 746-775
    Reactivity
    • 247
    • 126
    • 71
    • 19
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 222
    • 40
    • 4
    • 1
    Rabbit
    Clonality
    • 214
    • 53
    Polyclonal
    Conjugate
    • 114
    • 21
    • 19
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    This PDGFRA antibody is un-conjugated
    Application
    • 179
    • 113
    • 71
    • 54
    • 54
    • 41
    • 38
    • 24
    • 23
    • 14
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 746-775 amino acids from human PDGFRA.
    Clone
    RB11119
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDGFRA Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Alternative Name
    PDGFRA (PDGFRA Products)
    Synonyms
    AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
    Background
    PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
    Molecular Weight
    122670
    Gene ID
    5156
    NCBI Accession
    NP_006197
    UniProt
    P16234
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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