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ANTXR1 antibody (AA 358-386)

ANTXR1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB15324 unconjugated
Catalog No. ABIN2841879
  • Target See all ANTXR1 Antibodies
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 358-386
    Reactivity
    • 76
    • 40
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 70
    • 3
    • 3
    Rabbit
    Clonality
    • 73
    • 3
    Polyclonal
    Conjugate
    • 35
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANTXR1 antibody is un-conjugated
    Application
    • 48
    • 30
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
    Clone
    RB15324
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ANTXR1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Alternative Name
    ANTXR1 (ANTXR1 Products)
    Synonyms
    ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
    Background
    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
    Molecular Weight
    62789
    Gene ID
    84168
    NCBI Accession
    NP_060623, NP_115584, NP_444262
    UniProt
    Q9H6X2
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