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BACE1 antibody (AA 476-501)

BACE1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB7137 unconjugated
Catalog No. ABIN2841901
  • Target See all BACE1 Antibodies
    BACE1 (Beta-secretase 1 (BACE1))
    Binding Specificity
    • 16
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 476-501
    Reactivity
    • 83
    • 52
    • 41
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 77
    • 11
    Rabbit
    Clonality
    • 72
    • 16
    Polyclonal
    Conjugate
    • 57
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE1 antibody is un-conjugated
    Application
    • 65
    • 37
    • 29
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This BACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-501 amino acids from human BACE.
    Clone
    RB7137
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BACE1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    BACE1 (Beta-secretase 1 (BACE1))
    Alternative Name
    BACE (BACE1 Products)
    Synonyms
    ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
    Background
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
    Molecular Weight
    55764
    Gene ID
    23621
    NCBI Accession
    NP_001193978, NP_036236, NP_620427, NP_620428, NP_620429
    UniProt
    P56817
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