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NEK1 antibody (C-Term)

NEK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB2957 unconjugated
Catalog No. ABIN2842149
  • Target See all NEK1 Antibodies
    NEK1 (NIMA-Related Kinase 1 (NEK1))
    Binding Specificity
    • 15
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1165-1196, C-Term
    Reactivity
    • 29
    • 22
    • 15
    • 2
    Human
    Host
    • 44
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEK1 antibody is un-conjugated
    Application
    • 27
    • 17
    • 13
    • 13
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This NEK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1165-1196 amino acids from the C-terminal region of human NEK1.
    Clone
    RB2957
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NEK1 Primary Antibody
  • Application Notes
    WB: 1:500. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    NEK1 (NIMA-Related Kinase 1 (NEK1))
    Alternative Name
    NEK1 (NEK1 Products)
    Synonyms
    D8Ertd790e antibody, kat antibody, NY-REN-55 antibody, SRPS2 antibody, SRPS2A antibody, ATNEK1 antibody, F20D21.32 antibody, F20D21_32 antibody, NIMA-RELATED KINASE1 antibody, NIMA-related serine/threonine kinase 1 antibody, NIMA (never in mitosis gene a)-related expressed kinase 1 antibody, NIMA related kinase 1 antibody, NIMA-related kinase 1 antibody, NIMA-related serine/threonine kinase 1 antibody, Nek1 antibody, NEK1 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
    Molecular Weight
    142828
    Gene ID
    4750
    NCBI Accession
    NP_001186326, NP_001186327, NP_001186328, NP_001186329, NP_036356
    UniProt
    Q96PY6
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