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BRSK1 antibody (C-Term)

BRSK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB5415 unconjugated
Catalog No. ABIN2842239
  • Target See all BRSK1 Antibodies
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Binding Specificity
    • 15
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 654-684, C-Term
    Reactivity
    • 62
    • 32
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 84
    Rabbit
    Clonality
    • 83
    • 1
    Polyclonal
    Conjugate
    • 24
    • 9
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRSK1 antibody is un-conjugated
    Application
    • 58
    • 44
    • 18
    • 15
    • 13
    • 13
    • 12
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human BRSK1.
    Clone
    RB5415
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BRSK1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Alternative Name
    BRSK1 (BRSK1 Products)
    Synonyms
    BRSK1 antibody, hSAD1 antibody, Gm1100 antibody, SAD-B antibody, SADB antibody, RGD1563268 antibody, Sad-b antibody, BR serine/threonine kinase 1 antibody, BRSK1 antibody, Brsk1 antibody
    Background
    BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis.
    Molecular Weight
    85087
    Gene ID
    84446
    NCBI Accession
    NP_115806
    UniProt
    Q8TDC3
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