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SFRP1 antibody (N-Term)

SFRP1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB21557 unconjugated
Catalog No. ABIN2842622
  • Target See all SFRP1 Antibodies
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Binding Specificity
    • 15
    • 11
    • 8
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-55, N-Term
    Reactivity
    • 61
    • 48
    • 40
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 76
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 78
    • 11
    Polyclonal
    Conjugate
    • 29
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFRP1 antibody is un-conjugated
    Application
    • 67
    • 32
    • 31
    • 13
    • 13
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.
    Clone
    RB21557
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SFRP1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Zang, Zhang, Gao, Huang: "Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).

    Chang, Lei, Qin, Zeng, Zhang, Jin, Wang, Wang, Su: "Expression and prognostic value of SFRP1 and β-catenin in patients with glioblastoma." in: Oncology letters, Vol. 11, Issue 1, pp. 69-74, (2016) (PubMed).

    Zhou, Chen, Mashrah, Zhu, Liu, Yang, He, Wang, Xiang, Yao, Guo, Yang, Zhang: "Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis." in: OncoTargets and therapy, Vol. 8, pp. 2923-31, (2015) (PubMed).

  • Target
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Alternative Name
    SFRP1 (SFRP1 Products)
    Synonyms
    FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP2 antibody, 2210415K03Rik antibody, AW011917 antibody, AW107218 antibody, AW742929 antibody, sFRP-1 antibody, CSFRP1 antibody, SFRP1 antibody, XfrzA antibody, frp antibody, frp-1 antibody, frp1 antibody, frzA antibody, sarp2 antibody, sfrp1 antibody, LOC100231868 antibody, Srfp1a antibody, wu:fd19b09 antibody, secreted frizzled related protein 1 antibody, secreted frizzled-related protein 1 antibody, Secreted frizzled-related protein 1 antibody, secreted frizzled-related protein 1a antibody, secreted frizzled-related protein 1b antibody, SFRP1 antibody, Sfrp1 antibody, sfrp1 antibody, sfrp1a antibody, sfrp1b antibody
    Background
    SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer.
    Molecular Weight
    35386
    Gene ID
    6422
    NCBI Accession
    NP_003003
    UniProt
    Q8N474
    Pathways
    WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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