ITGA8 antibody (C-Term)

Catalog No. ABIN2845042

Product Details anti-ITGA8 Antibody

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Binding Specificity: AA 1025-1053, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.

Clone: RB20555

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ITGA8

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Alternative Name: ITGA8 (ITGA8 Products)

Synonyms: AI447669 antibody, RGD1564327 antibody, integrin alpha 8 antibody, integrin subunit alpha 8 antibody, Itga8 antibody, ITGA8 antibody

Background: Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.

Molecular Weight: 117474

Gene ID: 8516

NCBI Accession: NP_003629

UniProt: P53708