EIF3CL antibody (N-Term)

Catalog No. ABIN2845804

Product Details anti-EIF3CL Antibody

Target: EIF3CL (Eukaryotic Translation Initiation Factor 3, Subunit C-Like (EIF3CL))

Binding Specificity: AA 127-155, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3CL antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EIF3CL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the N-terminal region of human EIF3CL.

Clone: RB32067

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: EIF3CL Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for EIF3CL

Target: EIF3CL (Eukaryotic Translation Initiation Factor 3, Subunit C-Like (EIF3CL))

Alternative Name: EIF3CL (EIF3CL Products)

Synonyms: eukaryotic translation initiation factor 3 subunit C like antibody, EIF3CL antibody

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Molecular Weight: 105344

Gene ID: 8663

NCBI Accession: NP_001032897, NP_001186071, NP_001254503, NP_003743

UniProt: Q99613