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BCL2A1 antibody (Ala1)

BCL2A1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1251 unconjugated
Catalog No. ABIN2846124
  • Target See all BCL2A1 Antibodies
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Binding Specificity
    • 9
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-65, Ala1
    Reactivity
    • 50
    • 20
    • 12
    • 2
    • 2
    • 1
    Human
    Host
    • 47
    • 3
    • 1
    Rabbit
    Clonality
    • 40
    • 11
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BCL2A1 antibody is un-conjugated
    Application
    • 31
    • 22
    • 15
    • 9
    • 5
    • 4
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This BCL2A1 (A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-65 amino acids from human BCL2A1 (A1).
    Clone
    RB1251
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Gollob, Sciambi, Huang, Dressman: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." in: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).

  • Target
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Alternative Name
    BCL2A1 (BCL2A1 Products)
    Synonyms
    ACC-1 antibody, ACC-2 antibody, BCL2L5 antibody, BFL1 antibody, GRS antibody, HBPA1 antibody, Bcl2a1d antibody, BCL2A1 antibody, BCL2 related protein A1 antibody, BCL2-related protein A1 antibody, BCL2A1 antibody, Bcl2a1 antibody
    Background
    Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
    Molecular Weight
    20132
    Gene ID
    597
    NCBI Accession
    NP_001108207, NP_004040
    UniProt
    Q16548
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