HBG1 antibody (AA 56-85)

Catalog No. ABIN2846615

Product Details anti-HBG1 Antibody

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Binding Specificity: AA 56-85

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.

Clone: RB33610

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HBG1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for HBG1

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Alternative Name: HBG1 (HBG1 Products)

Synonyms: Hbe1 antibody, Hbb-y antibody, HBGA antibody, HBGR antibody, HSGGL1 antibody, beta-globin antibody, hbb1 antibody, hbga antibody, hbgr antibody, hsggl1 antibody, HBG2 antibody, HBG1 antibody, hemoglobin subunit gamma 1 antibody, hemoglobin subunit gamma 1 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma-1 antibody, Hbg1 antibody, HBG1 antibody, hbg1.L antibody, LOC100982657 antibody

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Molecular Weight: 16140

Gene ID: 3047

NCBI Accession: NP_000550

UniProt: P69891