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GABARAPL2 antibody

GABARAPL2 Reactivity: Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB22734 unconjugated
Catalog No. ABIN2849726
  • Target See all GABARAPL2 Antibodies
    GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
    Reactivity
    • 89
    • 24
    • 14
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Mouse
    Host
    • 90
    • 2
    Rabbit
    Clonality
    • 89
    • 3
    Polyclonal
    Conjugate
    • 28
    • 12
    • 12
    • 11
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABARAPL2 antibody is un-conjugated
    Application
    • 56
    • 54
    • 43
    • 14
    • 14
    • 9
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
    Clone
    RB22734
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GABARAPL2 Primary Antibody
  • Application Notes
    WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Delaney, Patel, Willis, Haghighiabyaneh, Axelrod, Tancioni, Lu, Bapat, Young, Cadassou, Bartakova, Sheth, Haft, Hui, Saenz, Schlaepfer, Harismendy, Stupack: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).

    Orfali, ODonovan, Nyhan, Britschgi, Tschan, Cahill, Mongan, Gudas, McKenna: "Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation." in: Experimental hematology, Vol. 43, Issue 9, pp. 781-93.e2, (2015) (PubMed).

  • Target
    GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
    Alternative Name
    GABARAPL2 (GABARAPL2 Products)
    Synonyms
    GABARAPL2 antibody, atg8 antibody, gef2 antibody, gate16 antibody, gate-16 antibody, Gef2 antibody, ATG8 antibody, ATG8C antibody, GATE-16 antibody, GATE16 antibody, GEF-2 antibody, GEF2 antibody, zgc:92319 antibody, 0610012F20Rik antibody, 2900019O08Rik antibody, AI173605 antibody, GABA type A receptor associated protein like 2 antibody, GABA(A) receptor-associated protein like 2 antibody, GABA(A) receptor-associated protein like 2 L homeolog antibody, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 antibody, GABARAPL2 antibody, gabarapl2 antibody, Gabarapl2 antibody, gabarapl2.L antibody
    Background
    Membrane proteins located on vesicles (v-SNAREs) and on the target membrane (t-SNAREs) mediate specific recognition and, possibly, fusion between a transport vesicle and its target membrane. The activity of SNARE molecules is regulated by several soluble cytosolic proteins. We have cloned a bovine brain cDNA encoding a conserved 117 amino acid polypeptide, denoted Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), that functions as a soluble transport factor. GATE-16 interacts with N-ethylmaleimidesensitive factor (NSF) and significantly stimulates its ATPase activity. It also interacts with the Golgi v-SNARE GOS-28 in an NSF-dependent manner. We propose that GATE-16 modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.
    Molecular Weight
    13667
    Gene ID
    11345
    NCBI Accession
    NP_009216
    UniProt
    P60520
    Pathways
    Autophagy
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