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ABI1 antibody

ABI1 Reactivity: Human, Mouse, Hamster WB, IP, IHC (p) Host: Mouse Monoclonal 1B9 unconjugated
Catalog No. ABIN1449186
  • Target See all ABI1 Antibodies
    ABI1 (Abl-Interactor 1 (ABI1))
    Reactivity
    • 62
    • 46
    • 36
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Hamster
    Host
    • 77
    • 2
    Mouse
    Clonality
    • 77
    • 2
    Monoclonal
    Conjugate
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABI1 antibody is un-conjugated
    Application
    • 60
    • 23
    • 15
    • 14
    • 14
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts with Abi-1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Hamster
    Purification
    Protein A agarose
    Immunogen
    Human recombinant Abi-1 expressed in E. coli
    Clone
    1B9
    Isotype
    IgG1
    Top Product
    Discover our top product ABI1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    ABI1 (Abl-Interactor 1 (ABI1))
    Alternative Name
    ABI1 / SSH3BP1 (ABI1 Products)
    Synonyms
    ABI-1 antibody, ABLBP4 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, NAP1 antibody, Ssh3bp1 antibody, E3b1 antibody, abi1 antibody, wu:fc66g09 antibody, wu:fk56a10 antibody, zgc:73174 antibody, MGC84356 antibody, ABI1 antibody, abi-1 antibody, e3b1 antibody, nap1bp antibody, ssh3bp antibody, ssh3bp1 antibody, wu:fe48a10 antibody, zgc:153534 antibody, DKFZp469P1319 antibody, abl interactor 1 antibody, abl-interactor 1 antibody, abl-interactor 1a antibody, abl interactor 1 S homeolog antibody, abl-interactor 1b antibody, Abl-interactor 1 antibody, Abl interactor 1 antibody, ABI1 antibody, Abi1 antibody, abi1a antibody, abi1.S antibody, abi1 antibody, abi1b antibody, Bm1_44660 antibody, LOAG_04356 antibody
    Background
    Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1
    Molecular Weight
    65 kDa
    Gene ID
    10006
    NCBI Accession
    NP_001012768
    UniProt
    Q8IZP0
    Pathways
    RTK Signaling, Response to Water Deprivation, ER-Nucleus Signaling
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