TNFRSF13C antibody (FITC)

Catalog No. ABIN2853608

Product Details anti-TNFRSF13C Antibody (FITC)

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF13C antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: This antibody reacts with human CD268/BAFF-R/BR3.

Purification: Protein A agarose

Immunogen: Human CD268/BAFF-R/BR3 transfectant

Clone: 8A7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 1 % BSA and 0.09 % NaN3

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C.

Target Details for TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Alternative Name: CD268 / BAFFR (TNFRSF13C Products)

Synonyms: RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody

Background: BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF-R/BR3, BCMA and TACI. BAFF-R/BR3 is the principal receptor for B cell survival and responses induced by BAFF.Synonyms: B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C

Gene ID: 115650

NCBI Accession: NP_443177

UniProt: Q96RJ3

Pathways: NF-kappaB Signaling