MVK antibody

Catalog No. ABIN2854359

Product Details anti-MVK Antibody

Target: MVK (Mevalonate Kinase (MVK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVK antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to MVK (mevalonate kinase)
MVK antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MVK. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MVK

Target: MVK (Mevalonate Kinase (MVK))

Alternative Name: mevalonate kinase (MVK Products)

Synonyms: F21A20.160 antibody, F21A20_160 antibody, MEVALONATE KINASE antibody, MVK antibody, mevalonate kinase antibody, DDBDRAFT_0168621 antibody, DDBDRAFT_0302479 antibody, DDB_0168621 antibody, DDB_0302479 antibody, LRBP antibody, MK antibody, MVLK antibody, POROK3 antibody, 2310010A05Rik antibody, AI256848 antibody, AI414037 antibody, zgc:103473 antibody, mevalonate kinase antibody, mvk antibody, hypothetical protein antibody, MVK antibody, MK antibody, MA_RS03165 antibody, PAB_RS02890 antibody, LMOf2365_0011 antibody, mvk antibody, RCI_RS14145 antibody, TGAM_RS08735 antibody, MMAH_RS07705 antibody, TAGG_RS01605 antibody, SHELL_RS02965 antibody, MVOL_RS03085 antibody, Igag_1464 antibody, VDIS_RS11260 antibody, MFER_RS04560 antibody, DESMU_RS01555 antibody, ARCVE_RS02955 antibody, MZHIL_RS05110 antibody, Mvk antibody

Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.

Cellular Localization: Cytoplasm , Peroxisome

Molecular Weight: 42 kDa

Gene ID: 4598

UniProt: Q03426