TP53BP2 antibody

Catalog No. ABIN2854394

Product Details anti-TP53BP2 Antibody

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ASPP2 (tumor protein p53 binding protein, 2)
ASPP2 antibody [C1C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human 53BP2 / ASPP2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: tumor protein p53 binding protein 2 (TP53BP2 Products)

Synonyms: 53BP2 antibody, ASPP2 antibody, BBP antibody, P53BP2 antibody, PPP1R13A antibody, TP53BP2 antibody, AI746547 antibody, Tp53bp2 antibody, X98550 antibody, Trp53bp2 antibody, wu:fa09h08 antibody, wu:fb04e08 antibody, zgc:85720 antibody, tumor protein p53 binding protein 2 antibody, tumor protein p53 binding protein 2 L homeolog antibody, tumor protein p53 binding protein, 2b antibody, transformation related protein 53 binding protein 2 antibody, tumor protein p53 binding protein, 2 antibody, tumor protein p53 binding protein, 2a antibody, TP53BP2 antibody, tp53bp2.L antibody, tp53bp2 antibody, tp53bp2b antibody, Trp53bp2 antibody, Tp53bp2 antibody, tp53bp2a antibody

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cytoplasm , perinuclear region , Nucleus

Molecular Weight: 126 kDa

Gene ID: 7159

UniProt: Q13625