Calpain 3 antibody (C-Term)

Catalog No. ABIN2854395

Product Details anti-Calpain 3 Antibody

Target: Calpain 3 (CAPN3)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Calpain 3 (calpain 3, (p94))
Calpain 3 antibody [C2C3], C-term

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Calpain 3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Calpain 3

Target: Calpain 3 (CAPN3)

Alternative Name: calpain 3 (CAPN3 Products)

Synonyms: capn3 antibody, MGC80925 antibody, zgc:92687 antibody, CAPN3 antibody, AI323605 antibody, Capa-3 antibody, Capa3 antibody, Lp82 antibody, p94 antibody, Lp84 antibody, Lp85 antibody, CANP3 antibody, CANPL3 antibody, LGMD2 antibody, LGMD2A antibody, nCL-1 antibody, SKM-CALP antibody, SKM-CALPOV antibody, nCL1 antibody, calpain 1, (mu/I) large subunit L homeolog antibody, calpain 3a, (p94) antibody, calpain 3 antibody, capn1.L antibody, capn3a antibody, CAPN3 antibody, Capn3 antibody

Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Cellular Localization: Cytoplasm

Molecular Weight: 94 kDa

Gene ID: 825

UniProt: P20807

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development