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ALAS2 antibody (Center)

ALAS2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854459
  • Target See all ALAS2 Antibodies
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Binding Specificity
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 46
    • 35
    • 32
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 37
    • 9
    Rabbit
    Clonality
    • 36
    • 10
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALAS2 antibody is un-conjugated
    Application
    • 34
    • 13
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine), Xenopus tropicalis
    Cross-Reactivity (Details)
    Rat (95 %), Xenopus laevis (81 %), Zebrafish (80 %), Bovine (95 %), Xenopus tropicalis (81 %)
    Characteristics
    Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)
    ALAS-E antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ALAS2 Primary Antibody
  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Comment

    Positive Control: Raji , K562 , HL60 , mouse liver

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Vercellotti, Khan, Nguyen, Chen, Bruzzone, Bechtel, Brown, Nath, Steer, Hebbel, Belcher: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).

  • Target
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Alternative Name
    ALAS-E (ALAS2 Products)
    Synonyms
    anh1 antibody, asb antibody, xlsa antibody, ALAS-E antibody, ALASE antibody, ANH1 antibody, ASB antibody, XLDPP antibody, XLEPP antibody, XLSA antibody, alas-e antibody, cb1063 antibody, sau antibody, sauternes antibody, ALAS antibody, Alas-2 antibody, 5'-aminolevulinate synthase 2 antibody, aminolevulinate, delta-, synthase 2 antibody, aminolevulinic acid synthase 2, erythroid antibody, alas2 antibody, ALAS2 antibody, Alas2 antibody, alas2.L antibody
    Background
    The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Mitochondrion matrix
    Molecular Weight
    65 kDa
    Gene ID
    212
    Pathways
    Transition Metal Ion Homeostasis
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