RASA3 antibody (C-Term)

Catalog No. ABIN2854563

Product Details anti-RASA3 Antibody

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to RASA3 (RAS p21 protein activator 3)
RASA3 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RASA3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Alternative Name: RAS p21 protein activator 3 (RASA3 Products)

Synonyms: rasa3 antibody, MGC82492 antibody, RASA3 antibody, gapiii antibody, gap1ip4bp antibody, LOC100222817 antibody, GAP1IP4BP antibody, GAPIII antibody, AI326412 antibody, C86362 antibody, E130011G04 antibody, scat antibody, R-ras gap antibody, RAS p21 protein activator 3 L homeolog antibody, RAS p21 protein activator 3 antibody, ras GTPase-activating protein 3 antibody, rasa3.L antibody, RASA3 antibody, rasa3 antibody, LOC100433573 antibody, Rasa3 antibody

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Cellular Localization: Cell membrane

Molecular Weight: 96 kDa

Gene ID: 22821

UniProt: Q14644