SNX15 antibody (C-Term)

Catalog No. ABIN2854564

Product Details anti-SNX15 Antibody

Target: SNX15 (Sorting Nexin 15 (SNX15))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX15 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Sorting nexin-15 (sorting nexin 15)
Sorting nexin-15 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SNX15. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: sorting nexin 15 (SNX15 Products)

Synonyms: SNX15 antibody, hsaf001435 antibody, snx15 antibody, MGC154249 antibody, HSAF001435 antibody, 1500032B08Rik antibody, E130013C21Rik antibody, sorting nexin 15 antibody, sorting nexin 15 S homeolog antibody, SNX15 antibody, snx15.S antibody, snx15 antibody, Snx15 antibody

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.

Molecular Weight: 38 kDa

Gene ID: 29907

UniProt: Q9NRS6