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FCGR2B antibody (C-Term)

FCGR2B Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854679
  • Target See all FCGR2B Antibodies
    FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
    Binding Specificity
    • 19
    • 11
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 52
    • 22
    • 18
    • 5
    • 1
    Human
    Host
    • 45
    • 6
    • 1
    Rabbit
    Clonality
    • 47
    • 5
    Polyclonal
    Conjugate
    • 22
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCGR2B antibody is un-conjugated
    Application
    • 46
    • 27
    • 17
    • 13
    • 13
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Rhesus Monkey
    Cross-Reactivity (Details)
    Rhesus Monkey (92 %)
    Characteristics
    Rabbit Polyclonal antibody to CD32B (Fc fragment of IgG, low affinity IIb, receptor (CD32))
    CD32B antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD32B. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product FCGR2B Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: THP-1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
    Alternative Name
    CD32B (FCGR2B Products)
    Synonyms
    CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody, Fc receptor, IgG, low affinity IIb antibody, low affinity immunoglobulin gamma Fc region receptor II antibody, FCGR2B antibody, Fcgr2b antibody, LOC100856270 antibody
    Background
    The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cell membrane, Single-pass type I membrane protein
    Molecular Weight
    34 kDa
    Gene ID
    2213
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling
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