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RHOC antibody

RHOC Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854791
  • Target See all RHOC Antibodies
    RHOC (Ras Homolog Gene Family, Member C (RHOC))
    Reactivity
    • 44
    • 19
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 9
    Rabbit
    Clonality
    • 37
    • 7
    Polyclonal
    Conjugate
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RHOC antibody is un-conjugated
    Application
    • 33
    • 28
    • 17
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to RhoC (ras homolog gene family, member C)
    RhoC antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RhoC. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product RHOC Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A431 , Mouse liver

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RHOC (Ras Homolog Gene Family, Member C (RHOC))
    Alternative Name
    ras homolog family member C (RHOC Products)
    Synonyms
    ARHC antibody, LOC100221682 antibody, ARH9 antibody, H9 antibody, RHOH9 antibody, AI324259 antibody, Arh9 antibody, Arhc antibody, CRHOC antibody, ras homolog family member C L homeolog antibody, ras homolog family member C antibody, rhoc.L antibody, RHOC antibody, rhoc antibody, Rhoc antibody
    Background
    This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side
    Molecular Weight
    22 kDa
    Gene ID
    389
    UniProt
    P08134
    Pathways
    WNT Signaling, Cell-Cell Junction Organization
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