HLAG antibody
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- Target See all HLAG Antibodies
- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HLAG antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit polyclonal antibody to HLA-G (major histocompatibility complex, class I, G)
HLA-G antibody [N1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human HLA-G. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product HLAG Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: Molt-4
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.83 mg/mL
- Buffer
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
- Alternative Name
- major histocompatibility complex, class I, G (HLAG Products)
- Synonyms
- MHC-G antibody, B-F antibody, B-F-S04 antibody, B-F-S05 antibody, B-F-S06 antibody, B-F-S07 antibody, B-FI antibody, B-FIV antibody, BF2 antibody, BFa2 antibody, BFw-03 antibody, BFw-05 antibody, BFz-01 antibody, major histocompatibility complex, class I, G antibody, MHC BF1 class I antibody, HLA-G antibody, BF1 antibody
- Background
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HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Cellular Localization: Membrane, Single-pass type I membrane protein - Molecular Weight
- 38 kDa
- Gene ID
- 3135
- UniProt
- P17693
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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