HBSAg antibody (Subtype ad/ay)

Catalog No. ABIN285504

Product Details anti-HBSAg Antibody

Key Features:

• Rabbit beta-Catenin antibody reliably detects beta-Catenin targets in Wnt-signaling using CUT&RUN, ICC, IF, WB, ELISA.
• Well suited to image adherens junctions in IHC/IF.
• Highly specific beta-Catenin detection in WB.

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Binding Specificity: Subtype ad/ay

Reactivity: Hepatitis B Virus (HBV)

Host: Goat

Clonality: Polyclonal

Conjugate: This HBSAg antibody is un-conjugated

Application: Please inquire

Immunogen: HBsAg antibody (Subtype ad/ay) was raised in goat using hepatitis B surface antigen as the immunogen.

Product Specific Information:

What can the beta-Catenin antibody ABIN2855042 be used for? This polyclonal, unconjugated rabbit anti-beta Catenin antibody is suitable for the detection of beta Catenin (CATNB, Catenin beta-1 or β-Catenin) by Chromatin Immunoprecipitation (ChIP), CUT&RUN, Immunofluorescence, ELISA, IHC and Western blotting. It has been validated for human, mouse, rat species. Additional predicted reactivities are chicken, pig, xenopus laevis, rhesus monkey and zebrafish.

What validation data is available for this beta-Catenin antibody? The beta Catenin antibody currently has an independent validation for CUT&RUN (Cleavage Under Targets and Release Using Nuclease) which can be read with protocol below. It has been used in seven publications, which are also indicated and can be found on PubMed. The rabbit beta Catenin antibody has 16 product images demonstrating its performance in CUT&RUN, Western blot, ICC / IF and IHC. Use our high-quality beta Catenin antibody to reliably detect beta Catenin for human and several other species.

What is the function of beta-Catenin? Beta Catenin is a key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of beta Catenin via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, beta Catenin is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. (UniProt) It is a hard target for ChIP-seq, but you can use our beta Catenin antibody / β-Catenin antibody in CUT&RUN.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Neat serum with no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles

Storage: -20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for HBSAg

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Alternative Name: HBsAg (HBsAg Products)

Target Type: Viral Protein