MIA3 antibody (N-Term)

Catalog No. ABIN2855189

Product Details anti-MIA3 Antibody

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (89 %)

Characteristics: Rabbit Polyclonal antibody to MIA3 (melanoma inhibitory activity family, member 3)
MIA3 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MIA3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 10 μg/mL* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)10 μg/mL* Western blot1:500-1:3000*

Comment:

Positive Control: A549 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.30 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MIA3

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Alternative Name: MIA3 (MIA3 Products)

Synonyms: CG11098 antibody, Dmel\\CG11098 antibody, TANGO1 antibody, MIA3 antibody, 9130229H14Rik antibody, A930039G15Rik antibody, AU022327 antibody, B230399H06Rik antibody, C80126 antibody, Gm1525 antibody, Tango antibody, ARNT antibody, D320 antibody, TANGO antibody, UNQ6077 antibody, Transport and Golgi organization 1 antibody, MIA family member 3, ER export factor antibody, melanoma inhibitory activity family, member 3 antibody, melanoma inhibitory activity protein 3 antibody, melanoma inhibitory activity family member 3 antibody, melanoma inhibitory activity 3 antibody, Tango1 antibody, MIA3 antibody, LOC100055507 antibody, mia3 antibody, Mia3 antibody

Background: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass type I membrane protein

Molecular Weight: 214 kDa

Gene ID: 375056