OTUB1 antibody (Center)

Catalog No. ABIN2855245

Product Details anti-OTUB1 Antibody

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Rat (Rattus), Pig (Porcine), Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Pig (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to OTUB1 (OTU domain, ubiquitin aldehyde binding 1)
OTUB1 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human OTUB1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.249 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for OTUB1

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Alternative Name: OTUB1 (OTUB1 Products)

Synonyms: OTB1 antibody, OTU1 antibody, AI850305 antibody, fa19h07 antibody, otub1 antibody, wu:fa19h07 antibody, zgc:92839 antibody, MGC131231 antibody, fb17f04 antibody, otub1l antibody, wu:fb17f04 antibody, zgc:92685 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1 antibody, OTU domain, ubiquitin aldehyde binding 1 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1b antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog antibody, similar to HSPC263 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1a antibody, OTUB1 antibody, Otub1 antibody, otub1b antibody, otub1.L antibody, otub1 antibody, RGD1565010 antibody, otub1a antibody

Background: The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.

Molecular Weight: 31 kDa

Gene ID: 55611