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COBRA1 antibody (Center)

COBRA1 Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855267
  • Target See all COBRA1 Antibodies
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 46
    • 15
    • 8
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 39
    • 7
    Rabbit
    Clonality
    • 41
    • 5
    Polyclonal
    Conjugate
    • 23
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COBRA1 antibody is un-conjugated
    Application
    • 35
    • 22
    • 7
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Characteristics
    Rabbit Polyclonal antibody to COBRA1 (cofactor of BRCA1)
    COBRA1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human COBRA1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: H1299

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    Alternative Name
    COBRA1 (COBRA1 Products)
    Synonyms
    LOC100219583 antibody, COBRA1 antibody, NELF-B antibody, bZ1O1.4 antibody, cobra1 antibody, cobra2 antibody, fe01e12 antibody, wu:fe01e12 antibody, zgc:55628 antibody, MGC131073 antibody, Cobra1 antibody, RGD1307832 antibody, A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Nelf-b antibody, cofactor of BRCA1 antibody, negative elongation factor complex member B antibody, negative elongation factor complex member B L homeolog antibody, LOC100219583 antibody, NELFB antibody, nelfb antibody, nelfb.L antibody, Nelfb antibody
    Background
    NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM]

    Cellular Localization: Nucleus
    Molecular Weight
    66 kDa
    Gene ID
    25920
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