ING1 antibody (C-Term)

Catalog No. ABIN2855405

Product Details anti-ING1 Antibody

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ING1 (inhibitor of growth family, member 1)
ING1 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ING1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: inhibitor of growth family member 1 (ING1 Products)

Synonyms: p24ING1c antibody, p33 antibody, p33ING1 antibody, p33ING1b antibody, p47 antibody, p47ING1a antibody, p33ING1c antibody, zgc:136918 antibody, ING1 antibody, 2610028J21Rik antibody, AA407184 antibody, AI875420 antibody, mING1h antibody, p33Ing1 antibody, p37Ing1b antibody, xing1 antibody, inhibitor of growth family member 1 antibody, inhibitor of growth family, member 1 antibody, inhibitor of growth family member 1 S homeolog antibody, ING1 antibody, Ing1 antibody, ing1 antibody, ing1.S antibody

Background: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Cellular Localization: Nucleus

Molecular Weight: 47 kDa

Gene ID: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy