SLC12A7 antibody (C-Term)

Catalog No. ABIN2855443

Product Details anti-SLC12A7 Antibody

Target: SLC12A7 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A7 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to KCC4 (solute carrier family 12 (potassium/chloride transporters), member 7)
KCC4 antibody [C2C3], C-term

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human KCC4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 4.71 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SLC12A7

Target: SLC12A7 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7))

Alternative Name: solute carrier family 12 member 7 (SLC12A7 Products)

Synonyms: SLC12A7 antibody, KCC4 antibody, Kcc4 antibody, Slc12a5 antibody, AA408796 antibody, D13Ertd261e antibody, solute carrier family 12 (potassium/chloride transporters), member 7 antibody, solute carrier family 12 member 7 antibody, solute carrier family 12, member 7 antibody, SLC12A7 antibody, Slc12a7 antibody

Background: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.

Cellular Localization: Membrane, Multi-pass membrane protein

Molecular Weight: 119 kDa

Gene ID: 10723

UniProt: Q9Y666