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KLF5 antibody

KO Validated KLF5 Reactivity: Human WB, IP, IF, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855604
  • Target See all KLF5 Antibodies
    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))
    Reactivity
    • 55
    • 52
    • 42
    • 14
    • 13
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 68
    • 4
    Rabbit
    Clonality
    • 70
    • 2
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This KLF5 antibody is un-conjugated
    Application
    • 45
    • 26
    • 26
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to KLF5 (Kruppel-like factor 5 (intestinal))
    KLF5 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human KLF5. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product KLF5 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: KLF5-transfected 293T , HeLa (500 μM CoCl2 treatment for 24 hr and 10 μM MG132 treatment for 2 hr)

    Validation: KO/KD, Orthogonal, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.8 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Sun, Li, Wang, Yue, Bai, Bian, Hao, Sun, Zhang, Liu: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." in: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).

    Ma, Chang, Zhao, Zhao, Xiong, Cao, Yuan, Zhang, Wang, Geng, Zheng, Li: "KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression." in: Scientific reports, Vol. 7, Issue 1, pp. 15683, (2019) (PubMed).

  • Target
    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))
    Alternative Name
    Kruppel like factor 5 (KLF5 Products)
    Synonyms
    KLF5 antibody, klf5 antibody, MGC115081 antibody, BTEB2 antibody, Bteb2 antibody, IKLF antibody, bteb2 antibody, 4930520J07Rik antibody, CKLF antibody, Kruppel like factor 5 antibody, Kruppel-like factor 5 (intestinal) S homeolog antibody, Kruppel-like factor 5 antibody, KLF5 antibody, klf5.S antibody, Klf5 antibody
    Background
    This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

    Cellular Localization: Nucleus
    Molecular Weight
    51 kDa
    Gene ID
    688
    UniProt
    Q13887
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