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DVL2 antibody (Internal Region)

DVL2 Reactivity: Human, Mouse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855718
  • Target See all DVL2 Antibodies
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Binding Specificity
    • 15
    • 15
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 67
    • 26
    • 23
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 64
    • 4
    Rabbit
    Clonality
    • 65
    • 3
    Polyclonal
    Conjugate
    • 30
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DVL2 antibody is un-conjugated
    Application
    • 65
    • 26
    • 20
    • 13
    • 12
    • 8
    • 6
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Rhesus Monkey
    Cross-Reactivity (Details)
    Rhesus Monkey (100 %)
    Characteristics
    Rabbit Polyclonal antibody to Dishevelled 2 (dishevelled, dsh homolog 2 (Drosophila))
    Dishevelled 2 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Dishevelled 2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product DVL2 Primary Antibody
  • Application Notes
    Suggested dilution Reference Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.04 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Rodriguez-Gil, Hu, Greer: "Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals." in: PLoS ONE, Vol. 8, Issue 2, pp. e56561, (2013) (PubMed).

  • Target
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Alternative Name
    Dishevelled 2 (DVL2 Products)
    Synonyms
    Xdsh antibody, dishevelled antibody, dsh antibody, dvl antibody, Dvl-2 antibody, xdsh antibody, wu:fc05d12 antibody, wu:fo71e09 antibody, wu:fp54a02 antibody, zgc:55372 antibody, dishevelled segment polarity protein 2 antibody, dishevelled segment polarity protein 2 L homeolog antibody, DVL2 antibody, dvl2 antibody, Dvl2 antibody, dvl2.L antibody
    Background
    This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

    Cellular Localization: Cytoplasm
    Molecular Weight
    79 kDa
    Gene ID
    1856
    Pathways
    Tube Formation
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