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UBA7 antibody (N-Term)

UBA7 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855770
  • Target See all UBA7 Antibodies
    UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 45
    • 2
    • 2
    Human
    Host
    • 45
    • 4
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBA7 antibody is un-conjugated
    Application
    • 28
    • 21
    • 20
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to UBE1L (ubiquitin-like modifier activating enzyme 7)
    UBE1L antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human UBE1L. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product UBA7 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
    Alternative Name
    ubiquitin like modifier activating enzyme 7 (UBA7 Products)
    Synonyms
    D8 antibody, UBA1B antibody, UBE1L antibody, UBE2 antibody, Ube1l antibody, 1300004C08Rik antibody, UBE1 antibody, xubc3 antibody, ubiquitin like modifier activating enzyme 7 antibody, ubiquitin-like modifier activating enzyme 7 antibody, ubiquitin conjugating enzyme E2 R2 S homeolog antibody, ubiquitin-like modifier-activating enzyme 7 antibody, UBA7 antibody, Uba7 antibody, ube2r2.S antibody, LOC100092397 antibody
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

    Molecular Weight
    112 kDa
    Gene ID
    7318
    UniProt
    P41226
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