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AKR1C1 antibody

DDH Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855775
  • Target See all AKR1C1 (DDH) Antibodies
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Reactivity
    • 35
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 6
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C1 antibody is un-conjugated
    Application
    • 22
    • 11
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to DHDH (dihydrodiol dehydrogenase (dimeric))
    DHDH antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human DHDH. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product DDH Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: DHDH transfected 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.99 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Alternative Name
    dihydrodiol dehydrogenase (DDH Products)
    Synonyms
    2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
    Background
    This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.

    Molecular Weight
    36 kDa
    Gene ID
    27294
    UniProt
    Q9UQ10
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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