TMEM59 antibody

Catalog No. ABIN2855840

Product Details anti-TMEM59 Antibody

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM59 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to TMEM59 (transmembrane protein 59)
TMEM59 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TMEM59. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , Mouse liver , rat kidney

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TMEM59

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Alternative Name: transmembrane protein 59 (TMEM59 Products)

Synonyms: Tmem59 antibody, C1orf8 antibody, HSPC001 antibody, 1110001M20Rik antibody, 3110046P06Rik antibody, AI256529 antibody, D4Ertd20e antibody, MTDCF1 antibody, ORF18 antibody, transmembrane protein 59 antibody, tmem59 antibody, Tmem59 antibody, TMEM59 antibody

Background: Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molecular Weight: 36 kDa

Gene ID: 9528

UniProt: Q9BXS4