CYP7B1 antibody (C-Term)
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- Target See all CYP7B1 Antibodies
- CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP7B1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Characteristics
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Rabbit polyclonal antibody to CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1)
CYP7B1 antibody [C3], C-term - Purification
- Affinity purified by Protein A.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CYP7B1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CYP7B1 Primary Antibody
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- Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Comment
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Positive Control: 293T , A431 , H1299
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
- Alternative Name
- CYP7B1 (CYP7B1 Products)
- Synonyms
- CYP7B1 antibody, CBAS3 antibody, CP7B antibody, SPG5A antibody, AW261589 antibody, D3Ertd552e antibody, hct-1 antibody, cytochrome P450 family 7 subfamily B member 1 antibody, cytochrome P450, family 7, subfamily B, polypeptide 1 antibody, cytochrome P450, family 7, subfamily b, polypeptide 1 antibody, CYP7B1 antibody, cyp7b1 antibody, Cyp7b1 antibody
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane - Molecular Weight
- 58 kDa
- Gene ID
- 9420
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling
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