PTPN14 antibody (C-Term)

Catalog No. ABIN2856182

Product Details anti-PTPN14 Antibody

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Pez (protein tyrosine phosphatase, non-receptor type 14)
Pez antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Pez. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PTPN14

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Alternative Name: protein tyrosine phosphatase non-receptor type 14 (PTPN14 Products)

Synonyms: PEZ antibody, PTP36 antibody, C130080N23Rik antibody, OTTMUSG00000022087 antibody, protein tyrosine phosphatase, non-receptor type 14 antibody, PTPN14 antibody, Ptpn14 antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.

Cellular Localization: Cytoplasm , cytoskeleton

Molecular Weight: 135 kDa

Gene ID: 5784

UniProt: Q15678