KPNA4 antibody (C-Term)

Catalog No. ABIN2856326

Product Details anti-KPNA4 Antibody

Target: KPNA4 (Importin Subunit alpha-3 (KPNA4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to KPNA4 (karyopherin alpha 4 (importin alpha 3))
KPNA4 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KPNA4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , HepG2 , Molt-4 , Rat2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.04 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-KPNA4 antibody (ABIN2856326)

Yang, Chiang, Chen, Lee, Wu, Tsou, Yang, Chang, Lin: "Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)." in: Journal of biomedical science, Vol. 22, pp. 33, (2016) (PubMed).

Target Details for KPNA4

Target: KPNA4 (Importin Subunit alpha-3 (KPNA4))

Alternative Name: karyopherin subunit alpha 4 (KPNA4 Products)

Synonyms: IPOA3 antibody, QIP1 antibody, SRP3 antibody, karyopherin subunit alpha 4 antibody, KPNA4 antibody

Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Molecular Weight: 58 kDa

Gene ID: 3840

UniProt: O00629