EIF2S2 antibody

Catalog No. ABIN2856393

Product Details anti-EIF2S2 Antibody

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2S2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Knockdown/Knockout validation was supported by references (PMID:26990993)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to EIF2 beta (eukaryotic translation initiation factor 2, subunit 2 beta, 38 kDa)
EIF2 beta antibody

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF2 beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , Mouse liver , PC-12 , Rat2

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EIF2S2

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Alternative Name: eukaryotic translation initiation factor 2 subunit beta (EIF2S2 Products)

Synonyms: EIF2 antibody, EIF2B antibody, EIF2beta antibody, PPP1R67 antibody, eIF-2-beta antibody, 2810026E11Rik antibody, 38kDa antibody, AA408636 antibody, AA571381 antibody, AA986487 antibody, AW822225 antibody, D2Ertd303e antibody, zgc:77084 antibody, wu:fc26g03 antibody, wu:fu10f07 antibody, MGC130959 antibody, DDBDRAFT_0205105 antibody, DDBDRAFT_0234112 antibody, DDB_0205105 antibody, DDB_0234112 antibody, AO090005001412 antibody, eukaryotic translation initiation factor 2 subunit beta antibody, eukaryotic translation initiation factor 2, subunit 2 (beta) antibody, eukaryotic translation initiation factor 2, subunit 2 beta antibody, eukaryotic translation initiation factor 2 subunit beta L homeolog antibody, eIF-3 beta antibody, hypothetical protein antibody, eukaryotic translation initiation factor 2 subunit 2 antibody, EIF2S2 antibody, Eif2s2 antibody, eif2s2 antibody, eif2s2.L antibody, eIF2s2 antibody, TP02_0678 antibody, EDI_093670 antibody, AOR_1_2450174 antibody, MGYG_05853 antibody, PGTG_10708 antibody, LOC101111733 antibody

Background: Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

Molecular Weight: 38 kDa

Gene ID: 8894

UniProt: P20042