HPS3 antibody (C-Term)

Catalog No. ABIN2856536

Product Details anti-HPS3 Antibody

Target: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Pig (Porcine), Cow (Bovine)

Cross-Reactivity (Details): Pig (92 %), Bovine (92 %)

Characteristics: Rabbit Polyclonal antibody to HPS3 (Hermansky-Pudlak syndrome 3)
HPS3 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HPS3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HPS3

Target: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Alternative Name: HPS3 (HPS3 Products)

Synonyms: SUTAL antibody, HPS3 antibody, coa antibody, HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 antibody, HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 L homeolog antibody, Hermansky-Pudlak syndrome 3 antibody, HPS3 antibody, hps3.L antibody, Hps3 antibody

Background: This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.

Cellular Localization: Cytoplasm

Molecular Weight: 114 kDa

Gene ID: 84343