MAP4K5 antibody

Catalog No. ABIN2856668

Product Details anti-MAP4K5 Antibody

Target: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to KHS (mitogen-activated protein kinase kinase kinase kinase 5)
KHS antibody [N3C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human KHS. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MAP4K5

Target: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Alternative Name: mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5 Products)

Synonyms: GCKR antibody, KHS antibody, KHS1 antibody, MAPKKKK5 antibody, 4432415E19Rik antibody, RGD1562028 antibody, fl74c10 antibody, wu:fl74c10 antibody, zgc:55719 antibody, zgc:55985 antibody, mitogen-activated protein kinase kinase kinase kinase 5 antibody, mitogen-activated protein kinase kinase kinase kinase 5 S homeolog antibody, MAP4K5 antibody, Map4k5 antibody, map4k5 antibody, map4k5.S antibody

Background: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Cellular Localization: Cytoplasm

Molecular Weight: 95 kDa

Gene ID: 11183

UniProt: Q9Y4K4