LRPPRC antibody

Catalog No. ABIN2856685

Product Details anti-LRPPRC Antibody

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to LRP130 (leucine-rich PPR-motif containing)
LRP130 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human LRP130. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299 , HeLa , mouse brain , 293T

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: leucine rich pentatricopeptide repeat containing (LRPPRC Products)

Synonyms: CLONE-23970 antibody, GP130 antibody, LRP130 antibody, LSFC antibody, Lrp157 antibody, 3110001K13Rik antibody, C76645 antibody, Gp130 antibody, Lrp130 antibody, Lsfc antibody, leucine rich pentatricopeptide repeat containing antibody, leucine-rich pentatricopeptide repeat containing antibody, leucine-rich PPR-motif containing antibody, LRPPRC antibody, Lrpprc antibody

Background: This gene encodes a protein that is leucine-rich and is thought to play a role in regulating the interaction of the cytoskeleton with a variety of cellular processes. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.

Cellular Localization: Mitochondrion , Nucleus , nucleoplasm , Nucleus inner membrane , Nucleus outer membrane

Molecular Weight: 158 kDa

Gene ID: 10128

UniProt: P42704