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Lamin B2 antibody

LMNB2 Reactivity: Human WB, IHC (p), IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856712
  • Target See all Lamin B2 (LMNB2) Antibodies
    Lamin B2 (LMNB2)
    Reactivity
    • 53
    • 40
    • 19
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 51
    • 17
    Rabbit
    Clonality
    • 48
    • 20
    Polyclonal
    Conjugate
    • 37
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lamin B2 antibody is un-conjugated
    Application
    • 49
    • 15
    • 14
    • 14
    • 13
    • 13
    • 11
    • 7
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to Lamin B2 (lamin B2)
    Lamin B2 antibody [N3C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Lamin B2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product LMNB2 Primary Antibody
  • Application Notes
    WB: 1:500-1:40000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.73 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Lamin B2 (LMNB2)
    Alternative Name
    lamin B2 (LMNB2 Products)
    Synonyms
    lmnb2-a antibody, LMNB2 antibody, lmn2 antibody, lamb2 antibody, Lamin-L(II) antibody, LOC100136040 antibody, im:7142331 antibody, lamin antibody, wu:fb94e05 antibody, wu:fb95e12 antibody, wu:fc15d06 antibody, wu:fc49h03 antibody, lamin-b2 antibody, lmnb2 antibody, LAMB2 antibody, LMN2 antibody, RGD1563803 antibody, lamin B2 S homeolog antibody, lamin B2 antibody, lamin B2 L homeolog antibody, lmnb2.S antibody, LMNB2 antibody, lmnb2 antibody, lmnb2.L antibody, Lmnb2 antibody
    Background
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.

    Cellular Localization: Nucleus inner membrane, Lipid-anchor, Nucleoplasmic side
    Molecular Weight
    68 kDa
    Gene ID
    84823
    UniProt
    Q03252
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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