ATP6V0A2 antibody (Internal Region)

Catalog No. ABIN2856744

Product Details anti-ATP6V0A2 Antibody

Target: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V0A2 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Rabbit Polyclonal antibody to ATP6V0A2 (ATPase, H+ transporting, lysosomal V0 subunit a2)
ATP6V0A2 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ATP6V0A2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*

Comment:

Positive Control: 3xFlag-human ATP6V0A2-transfected 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ATP6V0A2

Target: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Alternative Name: ATP6V0A2 (ATP6V0A2 Products)

Synonyms: A2 antibody, ARCL antibody, ARCL2A antibody, ATP6A2 antibody, ATP6N1D antibody, J6B7 antibody, RTF antibody, STV1 antibody, TJ6 antibody, TJ6M antibody, TJ6S antibody, VPH1 antibody, WSS antibody, 8430408C20Rik antibody, AI385560 antibody, ATP6a2 antibody, AW489264 antibody, Atp6n1d antibody, Atp6n2 antibody, C76904 antibody, ISF antibody, SHIF antibody, Stv1 antibody, TJ6s antibody, Tj6 antibody, V-ATPase 116 kDa antibody, V-ATPase a2 antibody, Cc1-3 antibody, J6b7 antibody, atp6v0a2 antibody, si:ch211-199i18.4 antibody, si:ch211-106a19.2 antibody, ATPase H+ transporting V0 subunit a2 antibody, ATPase, H+ transporting, lysosomal V0 subunit A2 antibody, ATPase, H+ transporting, lysosomal V0 subunit a2a antibody, ATPase, H+ transporting, lysosomal V0 subunit a2b antibody, ATP6V0A2 antibody, Atp6v0a2 antibody, atp6v0a2a antibody, atp6v0a2b antibody

Background: The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain, ATP6V0A2 is a component of the V(0) domain (Smith et al., 2003 [PubMed 14580332]).[supplied by OMIM]

Cellular Localization: Cell membrane, Multi-pass membrane protein , Endosome membrane

Molecular Weight: 98 kDa

Gene ID: 23545

Pathways: Transition Metal Ion Homeostasis, Proton Transport