MX1 antibody (Center)

Catalog No. ABIN2856789

Product Details anti-MX1 Antibody

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Rabbit Polyclonal antibody to MX1 (myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse))
MX1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MX1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-MX1 antibody (ABIN2856789)

Pryke, Abraham, Sali, Gall, Archer, Liu, Bambina, Baird, Gough, Chakhtoura, Haddad, Kirby, Nilsen, Streblow, Hirsch, Smith, DeFilippis: "A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses." in: mBio, Vol. 8, Issue 3, (2018) (PubMed).

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1 (MX1 Products)

Synonyms: IFI78 antibody, AI893580 antibody, Mx antibody, Mx-1 antibody, IFI-78K antibody, MX antibody, MxA antibody, Mx1-b antibody, Mx1B antibody, OGTPBP antibody, ONBP antibody, myxovirus (influenza virus) resistance 1 antibody, MX dynamin-like GTPase 1 antibody, MX dynamin like GTPase 1 antibody, Mx1 antibody, MX1 antibody

Background: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cytoplasm

Molecular Weight: 76 kDa

Gene ID: 4599