Oxytocin Receptor antibody

Catalog No. ABIN285883

Product Details anti-Oxytocin Receptor Antibody

Target: Oxytocin Receptor (OXTR)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oxytocin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: The OTR peptide is 100% conserved in Rat, 95% in Mouse, 89% in Sheep, 85% inHuman/monkey, 78% in Bovine, 80% in Pig. Antibody crossreactitivy in various species is no established.

Cross-Reactivity (Details): This OTR11 peptide sequence is 95 % conserved in mouse, 89 % in sheep, 85 % in human/monkey, 78 % with bovine, and 80 % with pig OTR.

Purification: Affinity chromatography purified

Immunogen: Oxytocin receptor antibody was raised in rabbit using a 20 amino acid peptide of rat OTR as the immunogen.

Isotype: IgG

Application Details

Application Notes: ELISA: 0.5-1 µg/mL,WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in PBS to 1 mg/mL

Concentration: Lot specific

Buffer: Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Oxytocin Receptor

Target: Oxytocin Receptor (OXTR)

Alternative Name: Oxytocin Receptor (OXTR Products)

Synonyms: OXTR antibody, OT-R antibody, OTR antibody, OTR1 antibody, oxytocin receptor antibody, OXTR antibody, Oxtr antibody

Target Type: Hormone

Background: The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin receptor is encoded by the OXTR gene, which has been localized to human chromosome 3p25. The OXTR protein belongs to the G-protein coupled receptor family, specifically Gq, and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate several different second messenger systems.

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour