Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN286590

Interleukin 7 Receptor (IL7R) antibody (Alexa Fluor 488)

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms ILRA, CD127, IL7RA, CDW127, IL-7R-alpha, IL-7Ralpha, IL-7RA, IL7R
Reactivity
»Alternatives Mouse (Murine)
Host
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Alexa Fluor 488
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN286590
Quantity 25 µg
Price
Contact our Customer Service for availability and price in your country.
Shipping to
Clone A7R34
Isotype IgG2a
Specificity The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL -7 receptor. IL -7 receptor alpha chain is expressed by immature B cells in the bone marrow, double -negative (CD4 -/CD8 -), single -positive (CD4+ and CD8+), but not double -positive (CD4+/CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL -7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL -7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127., Mouse
Alternative Name CD127
Application Notes This A7R34 antibody has been tested by flow cytometric analysis of mouse thymocyte and splenocyte suspensions. This can be used at less than or equal to 1 µg per million cells in a 100 µl total staining volume. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. This A7R34 antibody has been reported for use in flow cytometric analysis.
Restrictions For Research Use only
Buffer Phosphate buffer pH 7.2,150 mM NaCl, 0.09% NaN3, 0.1% gelatin
Preservative Sodium azide
Storage 4 °C
Araki, Turner, Shaffer et al.: "mTOR regulates memory CD8 T-cell differentiation." in: Nature, Vol. 460, Issue 7251, pp. 108-12, 2009 (PubMed).

Alternatives for antigen "Interleukin 7 Receptor (IL7R)", type "Antibodies"
Hosts (62), (45), (31), (3), (1)
Reactivities (96), (86), (35), (12), (12), (12), (12)
Applications (70), (52), (39), (20), (15), (8), (7), (5), (4), (2), (2), (2), (2), (2), (1)
Conjugates (13), (11), (8), (8), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (18), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Beacon