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UVRAG antibody (C-Term) (HRP)

UVRAG Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal HRP
Catalog No. ABIN2868805
  • Target See all UVRAG Antibodies
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Binding Specificity
    • 14
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 63
    • 38
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 4
    Rabbit
    Clonality
    • 61
    • 2
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UVRAG antibody is conjugated to HRP
    Application
    • 56
    • 21
    • 13
    • 12
    • 12
    • 10
    • 9
    • 9
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the C-terminal of human UVRAG
    Top Product
    Discover our top product UVRAG Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:1000 dilution of ABIN2868805 was sufficient for detection of UVRAG on 293T Rapamycin treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Alternative Name
    UVRAG (UVRAG Products)
    Synonyms
    DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody
    Background
    UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.
    Gene ID
    7405
    NCBI Accession
    NP_003360
    UniProt
    Q9P2Y5
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