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Dopamine d2 Receptor antibody (AA 9-21)

DRD2 Reactivity: Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN289417
  • Target See all Dopamine d2 Receptor (DRD2) Antibodies
    Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
    Binding Specificity
    • 15
    • 15
    • 9
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 9-21
    Reactivity
    • 67
    • 53
    • 47
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 72
    • 5
    Rabbit
    Clonality
    • 71
    • 5
    Polyclonal
    Conjugate
    • 33
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Dopamine d2 Receptor antibody is un-conjugated
    Application
    • 70
    • 33
    • 26
    • 26
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity (Details)
    This rat antigenic peptide is 100 % conserved in rat, pig, bovine, 92 % in mouse, and 78 % in human D1 (D1A/DRD1). No significant sequence homology exist with other dopamine receptors (D1B, D2-D5).
    Purification
    Affinity chromatography purified
    Immunogen
    Dopamine receptor 2 antibody was raised in rabbit using a 13 amino acid peptide of rat D1 R as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product DRD2 Primary Antibody
  • Application Notes
    ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    Dopamine Receptor 2 Blocking peptide, catalog no. 30R-AD007, is also available for use as a blocking control in assays to test for the specificity of this Dopamine Receptor 2 antibody.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
    Alternative Name
    Dopamine Receptor 2 (DRD2 Products)
    Synonyms
    D2DR antibody, D2R antibody, drd2b antibody, d2r2 antibody, Drd-2 antibody, d2dr antibody, d2r antibody, drd2 antibody, drd2-B antibody, DRD2 antibody, D2 antibody, CG18741 antibody, CG7569 antibody, DAMB antibody, DDR2 antibody, DOPR2 antibody, DOPR99B antibody, Dar2 antibody, Dmel\\CG18741 antibody, DopD1 antibody, DopR99B antibody, DopRII antibody, dopamine receptor D2 antibody, dopamine receptor D2 like antibody, dopamine receptor D2 L homeolog antibody, dopamine receptor D2 S homeolog antibody, Dopamine 1-like receptor 2 antibody, DRD2 antibody, drd2l antibody, drd2 antibody, Drd2 antibody, drd2.L antibody, drd2.S antibody, Dop1R2 antibody
    Background
    Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. The D1 subtype is the most abundant dopamine receptor in the central nervous system. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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