SLC5A1 antibody

Catalog No. ABIN289545

Product Details anti-SLC5A1 Antibody

Target: SLC5A1 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC5A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Pig (Porcine), Bird (Avian), Dog (Canine), Cat (Feline), Rabbit, Rat (Rattus), Reptile

Cross-Reactivity (Details): This mouse SG11 peptide sequence is 100 % conserved in rabbit, ovine, and sheep, 94 % in equine and rat, 89 % in pig, 84 % in human, 86 % in chicken SGLT-1. It also has high sequence homology with the low affinity SGLT- in mouse SGLT-4a/4b (84 % ), human SAAT1/SGLT-3 (78 % ), and SGLT-2 from human and rat (63 % ).

Purification: Affinity chromatography purified

Immunogen: SGLT1 antibody was raised in rabbit using a 19 amino acid peptide sequence of mouse/rabbit SGLT-1 as the immunogen.

Isotype: IgG

Application Details

Application Notes: ELISA: 0.5-1 µg/mL,WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in water.

Concentration: Lot specific

Buffer: Supplied as a lyophilized powder containing 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for SLC5A1

Target: SLC5A1 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1))

Alternative Name: SGLT1 (SLC5A1 Products)

Synonyms: D22S675 antibody, NAGT antibody, SGLT1 antibody, zgc:66074 antibody, zgc:85782 antibody, SLC5A1 antibody, Sglt1 antibody, solute carrier family 5 member 1 antibody, solute carrier family 5 (sodium/glucose cotransporter), member 1 antibody, SLC5A1 antibody, slc5a1 antibody, Slc5a1 antibody

Background: Sodium glucose co transporters (SGLT), are active in the reabsorption of glucose in the proximal tubules of the kidneys. In the kidney, SGLT1 is expressed in proximal tubule Sq1 segments. SGLT1/NAGT or SLC5A1/NAGT (rat/mouse 665 aa, human 664 aa, chromosome 22q13.1, ~75 kDa) is a high affinity, Na+-coupled, intestinal transporter responsible for active glucose transport across the brush border membrane.