AGEs antibody (Peroxidase)
| Antigen |
|
| Clonality |
Monoclonal (6D12) |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
Biotin (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Application
|
 Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|
| Catalog no. |
ABIN289932 |
| Quantity |
20 ug (0.1 mg/ml) |
| Price |
1,142.89 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Immunogen
|
AGEs-BSA
|
|
Format
|
Affinity-purified
|
|
Isotype
|
IgG1
|
|
Clone
|
6D12
|
|
Description
|
Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base and Amadori rearrangement products, to the formation ofadvanced glycation end products (AGEs). Recent immunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modifiedproteins in several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules in patients with diabetic nephropathy andchronic renal failure, diabetic retina, peripheral nerves of diabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulinforming amyloid fibrils in patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer
|
|
Application Notes
|
WB 0.25-5.0 ug/ml. IHC 2.0 ug/ml. ICC Not tested. ELISA 0.1-0.5 ug/ml. FCM Not tested. Neutralization Not tested. IP Not tested
|
|
Concentration
|
0.1 mg/ml
|
|
Purification
|
ProteinG Affinity Purified
|
|
Buffer
|
PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
|
|
Storage
|
Store below -20
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "AGEs", type "Antibodies"
|
Hosts
|
Rabbit (20), Mouse (2)
|
|
Reactivities
|
Human (19), Mouse (Murine) (15), Rat (Rattus) (15), All Species (2)
|
|
Applications
|
Immunofluorescence (IF) (18), ELISA (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoelectron Microscopy (IEM) (1), Western Blotting (WB) (1)
|
|
Conjugates
|
Biotin (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
